Sutter Instrument is proud to announce one of the most significant additions to our product lineup in years: a full suite of electrophysiology recording hardware and software.

The IPA® family of Integrated Patch Amplifiers, enables efficient, low-noise whole-cell recordings. The IPA system, available with one (IPA) or two recording channels (Double IPA), combines state-of-the-art amplifier technology with fully integrated D/A and A/D conversion and a high speed USB interface. Acquisition, data management, and streamlined analysis are performed using the bundled SutterPatchTM Data Acquisition and Analysis Software, built on the foundation of Igor Pro 8 (WaveMetrics, Inc.).

dPatch®
LOW-NOISE ULTRA-FAST DIGITAL PATCH CLAMP AMPLIFIER SYSTEM 

The dPatch Integrated Digital Patch Clamp Amplifier is a computer-controlled single- or dual-headstage amplifier optimized for both single-channel and whole-cell recording applications.

Amplifier

  • Hardware architecture enables all data conversion to be performed near the preparation, well away from known noise sources, such as power supplies and high-speed digital circuitry.
  • Voltage clamp and true current clamp modes with smart switching between modes to avoid current artifacts
  • Three choices of headstage feedback elements to optimize both single-channel and whole-cell recording
dPatch
d Patch

IPA® / DOUBLE IPA®
Integrated Patch Clamp Amplifiers with Data Acquisition System

Amplifier

  • Voltage clamp and true current clamp modes with smart switching between modes to avoid current artifacts
  • Open-Circuit (RMS) noise of 1.4 pA in a 0.1-10 kHz bandwidth
  • 500 MΩ headstage feedback resistor provides a max. range of ±20 nA
  • Fast pipette capacitance compensation and whole-cell compensation
    • Pipette capacitance compensation up to 25 pF
    • Whole-cell compensation: Cm from 1-100 pF ; Rs from 1-100 MΩ
  • Onboard automatic compensation routines
  • Series resistance prediction and correction (0-100 MΩ)
  • Four-pole Bessel low-pass filter (cutoff = 0.5 – 20 kHz)
  • Output gain: 1,2,5,10,20,50,100
  • Holding potential ±1000 mV
  • Current clamp bridge compensation and capacitance neutralization
  • Slow holding potential tracking compensates for drift during current clamp recordings
IPA DOUBLE IPA
IPA DOUBLE IPA

Data Acquisition

  • Embedded data acquisition system eliminates the need for an external data acquisition board and facilitates setup
  • Single high-speed USB connection controls data acquisition and amplifier
  • Up to 6 or 8 input channels (1 – 50 kHz sampling rate per channel)
  • Up to 400 kHz aggregate sampling rate (1-10 kHz sampling rate per channel)
  • Multi-amplifier mode: A combination of any two IPA or Double IPA Amplifiers can be connected, providing up to 16 input channels
  • Complex command waveforms
  • Auxiliary input / output for control of other instrumentation
    • 4 analog input channels (± 10 V)
    • 2 analog output channels (± 10 V)
    • 8 digital output channels (TTL)
  • Data acquisition can be initiated by an onboard microsecond clock or external (TTL) trigger

SutterPatch® Software

  • Built on the foundation of Igor Pro 8 (WaveMetrics, Inc.)
  • Paradigms and Routines provide complete experimental control
  • Waveform Editor for easy creation of even the most complex stimulus patterns or user-defined templates
  • Associated metadata stores all relevant information regarding your experiment
  • Comprehensive data analysis routines and publication quality graphics
  • Runs on Windows 7 or later (64-bit) or Mac OS X 10.11 (El Capitan) or later
Software2
software